Differential gene expression during early development in brains of wildtype and biotinidase-deficient mice
نویسندگان
چکیده
منابع مشابه
Differential gene expression during early development in brains of wildtype and biotinidase-deficient mice
Biotinidase deficiency is an autosomal recessively inherited disorder characterized by neurological and cutaneous abnormalities. Untreated individuals with biotinidase deficiency cannot recycle biotin from biocytin (N-biotinyl-ϵ-lysine), the proteolytic digestion product of protein-bound biotin. Biotin therapy can markedly resolve symptoms, or can prevent the development of symptoms if initiate...
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ژورنال
عنوان ژورنال: Molecular Genetics and Metabolism Reports
سال: 2016
ISSN: 2214-4269
DOI: 10.1016/j.ymgmr.2016.09.007